{"id":12289,"date":"2023-11-10T18:32:36","date_gmt":"2023-11-10T18:32:36","guid":{"rendered":"https:\/\/infundpros.com\/finance\/heres-how-eli-lilly-might-bring-a-game-changing-alzheimers-drug-to-market\/"},"modified":"2023-11-10T18:32:37","modified_gmt":"2023-11-10T18:32:37","slug":"heres-how-eli-lilly-might-bring-a-game-changing-alzheimers-drug-to-market","status":"publish","type":"post","link":"https:\/\/infundpros.com\/?p=12289","title":{"rendered":"Here\u2019s how Eli Lilly might bring a game-changing Alzheimer\u2019s drug to market"},"content":{"rendered":"<p>As part of the MarketWatch 50 series, Eleanor Laise interviewed Dr. Daniel Skovronsky, the chief scientific and medical officer at Eli Lilly &amp; Co.<br \/>\n        LLY,<br \/>\n        <bg-quote field=\"percentchange\" format=\"0,000.00%\" channel=\"\/zigman2\/quotes\/200106384\/composite\" class=\"positive\">+0.35%<\/bg-quote><span>.<\/span><br \/>\n       The company\u2019s stock has soared 63% this year amid excitement for its Mounjaro treatment for Type 2 diabetes. This is a GLP-1 medication, competing with Wegovy and Ozempic, which are made by Novo Nordisk A\/S<br \/>\n        NVO,<br \/>\n        <bg-quote field=\"percentchange\" format=\"0,000.00%\" channel=\"\/zigman2\/quotes\/203484366\/composite\" class=\"positive\">+0.69%<\/bg-quote><span>.<\/span><br \/>\n       This category of medicine leads to such dramatic weight loss that it could affect a number of other industries.<\/p>\n<div>\n<p>During the interview, Skovronsky talked about a different path ahead for much less expensive weight-loss drugs. He also said he was \u201d\u00a0extremely optimistic\u201d about Lilly\u2019s experimental treatment for Alzheimer\u2019s disease, which is going through clinical trials.<\/p>\n<div data-layout=\"inline\n                \" data-layout-mobile=\"\" class=\"\n          media-object\n          type-InsetMediaVideo\n            inline\n  article__inset\n          article__inset--type-InsetMediaVideo\n            article__inset--inline\n  \"><\/p>\n<p>          <!-- eventually when we know what this card will be we can change it and leave this one --><\/p>\n<figure class=\"media-object-video article__inset__video media-object-video--standard\"><figcaption class=\"wsj-article-caption article__inset__video__caption\">\n          These overlooked medications could be the GLP-1 drugs of the future.<br \/>\n        <\/figcaption><\/figure>\n<\/p><\/div>\n<p>More of the MarketWatch 50:<\/p>\n<h2>Earnings season can be brutal<\/h2>\n<p>Each quarterly earnings season features myriad headlines about companies whose results beat analysts\u2019 consensus estimates for sales and earnings. You can expect a roughly 70% \u201cbeat rate\u201d every quarter. Over the long term, a \u201cbeat and raise\u201d pattern, with consensus estimates rising following the earnings reports, can support rising stock prices.<\/p>\n<p>But there are always exceptions. A company might miss the expectations of analysts, even after lowering the bar with its previous guidance. Or a company might be forced to reduce its stated outlook because of operational difficulties or a changing market. Here are some examples from this week:<\/p>\n<p>Shares of Warner Bros. Discovery Inc.<br \/>\n        WBD,<br \/>\n        <bg-quote field=\"percentchange\" format=\"0,000.00%\" channel=\"\/zigman2\/quotes\/200511275\/composite\" class=\"positive\">+4.36%<\/bg-quote><br \/>\n       plunged 19% on Wednesday after the company warned that it will not be able to pay down debt as quickly as it had planned if the TV advertising market doesn\u2019t recover. Another factor that may have upset investors was a 700,000 decline in direct-to-consumer subscriptions.<\/p>\n<p>Warner Bros. Discovery CEO David Zaslav said during the company\u2019s earnings call that the subscription decline was tied to \u201cone of our lightest original-content schedules in years,\u201d partly resulting from the Hollywood actors strike, which ended Thursday. <\/p>\n<p>The company had $44.8 billion in total debt as of Sept. 30, down from $52.6 billion at the end of 2022. During the call, Zaslav said: \u201cWhile paying down debt and de-levering will remain a top priority for us, we\u2019re also now in a position to allocate more capital towards growth opportunities.\u201d<\/p>\n<p>WBD in its current form was created on April 8, 2022, when AT&amp;T Inc.<br \/>\n        T,<br \/>\n        <bg-quote field=\"percentchange\" format=\"0,000.00%\" channel=\"\/zigman2\/quotes\/203165245\/composite\" class=\"negative\">-0.32%<\/bg-quote><br \/>\n       divested WarnerMedia, which was merged with Discovery Inc. Here\u2019s a chart for the combined company\u2019s stock price since that date:<\/p>\n<div data-layout=\"inline\n                \" data-layout-mobile=\"\" class=\"\n          media-object\n          type-InsetMediaIllustration\n            inline\n  article__inset\n          article__inset--type-InsetMediaIllustration\n            article__inset--inline\n  \"><\/p>\n<p>          <!-- eventually when we know what this card will be we can change it and leave this one --><\/p>\n<figure class=\"\n        media-object-image\n        enlarge-image\n        img-inline\n        article__inset__image\n      \" itemscope=\"\" itemtype=\"http:\/\/schema.org\/ImageObject\"><\/p>\n<\/figure><\/div>\n<p>More examples of difficult earnings reports this week: <\/p>\n<h2>Earnings season and IPO buyers\u2019 remorse <\/h2>\n<p>There was a long period during which low interest rates helped support many initial public offerings, with shares often soaring on the first day of trading. That has changed, with a slow trickle of companies going public and a tepid response in the stock market. Earnings season has underscored the regrets among investors who jumped in early for several IPOs, including Arm Holdings PLC<br \/>\n        ARM,<br \/>\n        <bg-quote field=\"percentchange\" format=\"0,000.00%\" channel=\"\/zigman2\/quotes\/248039114\/composite\" class=\"positive\">+0.52%<\/bg-quote><span>,<\/span><br \/>\n       Klaviyo Inc.<br \/>\n        KVYO,<br \/>\n        <bg-quote field=\"percentchange\" format=\"0,000.00%\" channel=\"\/zigman2\/quotes\/248220343\/composite\" class=\"positive\">+1.08%<\/bg-quote><br \/>\n       and Instacart<br \/>\n        CART,<br \/>\n        <bg-quote field=\"percentchange\" format=\"0,000.00%\" channel=\"\/zigman2\/quotes\/248220340\/composite\" class=\"positive\">+3.15%<\/bg-quote><span>.<\/span>\n      <\/p>\n<h2>A different earnings-season tone from Disney<\/h2>\n<div data-layout=\"inline\n                \" data-layout-mobile=\"\" class=\"\n          media-object\n          type-InsetMediaIllustration\n            inline\n  article__inset\n          article__inset--type-InsetMediaIllustration\n            article__inset--inline\n  \"><\/p>\n<p>          <!-- eventually when we know what this card will be we can change it and leave this one --><\/p>\n<figure class=\"\n        media-object-image\n        enlarge-image\n        img-inline\n        article__inset__image\n      \" itemscope=\"\" itemtype=\"http:\/\/schema.org\/ImageObject\"><\/p>\n<\/figure><\/div>\n<p>Investors were in a better mood after Walt Disney Co.<br \/>\n        DIS,<br \/>\n        <bg-quote field=\"percentchange\" format=\"0,000.00%\" channel=\"\/zigman2\/quotes\/203410047\/composite\" class=\"negative\">-2.81%<\/bg-quote><br \/>\n       reported its third-quarter results, including a large increase in Disney+ streaming subscriptions. The company\u2019s stock rose 7% on Thursday for its best performance in almost three years, as analysts reacted positively to Disney CEO Bob Iger\u2019s cost-cutting initiatives and the increasing profitability with price increases. <\/p>\n<p>Disney\u2019s stock was still down 48% from two years earlier, with dividends reinvested, according to FactSet.<\/p>\n<p><strong>Therese Poletti: <\/strong>Disney CEO Bob Iger is getting his hands dirty as he focuses on studio woes \u2014 will be it enough?<\/p>\n<p>Positive reactions to other companies\u2019 earnings news:<\/p>\n<h2>New tax rules and advice for tax planning<\/h2>\n<div data-layout=\"inline\n                \" data-layout-mobile=\"\" class=\"\n          media-object\n          type-InsetMediaIllustration\n            inline\n  article__inset\n          article__inset--type-InsetMediaIllustration\n            article__inset--inline\n  \"><\/p>\n<p>          <!-- eventually when we know what this card will be we can change it and leave this one --><\/p>\n<figure class=\"\n        media-object-image\n        enlarge-image\n        img-inline\n        article__inset__image\n      \" itemscope=\"\" itemtype=\"http:\/\/schema.org\/ImageObject\"><\/p>\n<\/figure><\/div>\n<p>Andrew Kesher explains changes in tax brackets and rules for 2024:<\/p>\n<p>Beth Pinsker explains how to use the latest information from the IRS to lower your 2024 tax bill.<\/p>\n<h2>Stock picks<\/h2>\n<div data-layout=\"inline\n                \" data-layout-mobile=\"\" class=\"\n          media-object\n          type-InsetMediaIllustration\n            inline\n  article__inset\n          article__inset--type-InsetMediaIllustration\n            article__inset--inline\n  \"><\/p>\n<p>          <!-- eventually when we know what this card will be we can change it and leave this one --><\/p>\n<figure class=\"\n        media-object-image\n        enlarge-image\n        img-inline\n        article__inset__image\n      \" itemscope=\"\" itemtype=\"http:\/\/schema.org\/ImageObject\"><\/p>\n<\/figure><\/div>\n<p>When you see how people suffer from hurricanes or floods, you might wonder why anyone would choose to live in the affected areas. Michael Brush explains how to profit from peoples\u2019 location preferences over the long term.<\/p>\n<p>More about stocks:<\/p>\n<ul class=\"articleList\">\n<li>\n      Three value-stock picks from a veteran manager with a good performance record<\/p>\n<\/li>\n<li>\n      Five potential takeover targets in the oil industry, following deals by Exxon Mobil and Chevron<\/p>\n<\/li>\n<\/ul>\n<h2>Retirement planning<\/h2>\n<p>Alessandra Malito writes the Help Me Retire column. This week she assists a woman whose brother is 60 and has applied for Social Security disability benefits but still wants to contribute to a retirement account.<\/p>\n<p>More about retirement and related planning: <\/p>\n<ul class=\"articleList\">\n<li>\n      My husband leaves retirement-investing plans to me. How do I hire the right adviser? <\/p>\n<\/li>\n<li>\n      Medicare\u2019s Meena Seshamani answers your questions about open enrollment<\/p>\n<\/li>\n<\/ul>\n<h2>Stock market bulls and bears<\/h2>\n<div data-layout=\"inline\n                \" data-layout-mobile=\"\" class=\"\n          media-object\n          type-InsetMediaIllustration\n            inline\n  article__inset\n          article__inset--type-InsetMediaIllustration\n            article__inset--inline\n  \"><\/p>\n<p>          <!-- eventually when we know what this card will be we can change it and leave this one --><\/p>\n<figure class=\"\n        media-object-image\n        enlarge-image\n        img-inline\n        article__inset__image\n      \" itemscope=\"\" itemtype=\"http:\/\/schema.org\/ImageObject\"><\/p>\n<\/figure><\/div>\n<p>You may already be aware that the tech-oriented \u201cMagnificent Seven\u201d stocks \u2014 Apple Inc.<br \/>\n        AAPL,<br \/>\n        <bg-quote field=\"percentchange\" format=\"0,000.00%\" channel=\"\/zigman2\/quotes\/202934861\/composite\" class=\"positive\">+1.81%<\/bg-quote><span>,<\/span><br \/>\n       Microsoft Corp.<br \/>\n        MSFT,<br \/>\n        <bg-quote field=\"percentchange\" format=\"0,000.00%\" channel=\"\/zigman2\/quotes\/207732364\/composite\" class=\"positive\">+2.21%<\/bg-quote><span>,<\/span><br \/>\n       Alphabet Inc.<br \/>\n        GOOGL,<br \/>\n        <bg-quote field=\"percentchange\" format=\"0,000.00%\" channel=\"\/zigman2\/quotes\/202490156\/lastsale\" class=\"positive\">+1.60%<\/bg-quote><span>,<\/span><br \/>\n       Amazon.com Inc.<br \/>\n        AMZN,<br \/>\n        <bg-quote field=\"percentchange\" format=\"0,000.00%\" channel=\"\/zigman2\/quotes\/210331248\/composite\" class=\"positive\">+1.75%<\/bg-quote><span>,<\/span><br \/>\n       Nvidia Corp.<br \/>\n        NVDA,<br \/>\n        <bg-quote field=\"percentchange\" format=\"0,000.00%\" channel=\"\/zigman2\/quotes\/200467500\/composite\" class=\"positive\">+2.53%<\/bg-quote><span>,<\/span><br \/>\n       Meta Platforms Inc.<br \/>\n        META,<br \/>\n        <bg-quote field=\"percentchange\" format=\"0,000.00%\" channel=\"\/zigman2\/quotes\/205064656\/composite\" class=\"positive\">+1.97%<\/bg-quote><br \/>\n       and Tesla Inc.<br \/>\n        TSLA,<br \/>\n        <bg-quote field=\"percentchange\" format=\"0,000.00%\" channel=\"\/zigman2\/quotes\/203558040\/lastsale\" class=\"positive\">+1.90%<\/bg-quote><br \/>\n       \u2014 have been responsible for most of the S&amp;P 500\u2019s<br \/>\n        SPX<br \/>\n       15% gain this year. This is because the benchmark index is weighted by market capitalization.<\/p>\n<p>The three-year chart for the S&amp;P 500 information-technology sector, above, shows a feast-and-famine pattern, with a bit of a rough ride recently.<\/p>\n<p>But there are signs that technology stocks may rally through the end of 2023, as Joseph Adinolfi reports. And on Friday, he pointed to another bullish indicator.<\/p>\n<p>But there is never a shortage of warnings about financial markets. Here\u2019s a sampling:<\/p>\n<h2>You too can be a mortgage lender<\/h2>\n<p>In the Big Move column, Aarthi Swaminathan answers questions from a man who is renting out a house that he has owned for a long time. Now he wants to sell, and the renters want to buy the home. With interest rates so high, should he considering being the mortgage lender?<\/p>\n<p>More housing coverage:<\/p>\n<h2>A big bounceback in the stock market, and 13 candidates for recovery in 2024<\/h2>\n<p>Mark Hulbert points out that Salesforce Inc.<br \/>\n        CRM,<br \/>\n        <bg-quote field=\"percentchange\" format=\"0,000.00%\" channel=\"\/zigman2\/quotes\/200515854\/composite\" class=\"positive\">+1.62%<\/bg-quote><br \/>\n       \u2014 last year\u2019s worst performer among the 30 components of the Dow Jones Industrial Average<br \/>\n        DJIA<br \/>\n       \u2014 has been this year\u2019s best-performing stock in the venerable index.<\/p>\n<p>Among this year\u2019s worst-performing stocks in the S&amp;P 500, here are Hulbert\u2019s 13 candidates for recovery in 2024.<\/p>\n<p><strong>Want more from MarketWatch? Sign up for this and\u00a0other newsletters\u00a0to get the latest news and advice on personal finance and investing.<\/strong><\/p>\n<\/p><\/div>\n<p>Read the full article <a href=\"https:\/\/www.marketwatch.com\/story\/heres-how-eli-lilly-might-bring-a-game-changing-alzheimers-drug-to-market-6895dbc5?mod=personal-finance\" target=\"_blank\" rel=\"noopener\">here<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>As part of the MarketWatch 50 series, Eleanor Laise interviewed Dr. Daniel Skovronsky, the chief scientific and medical officer at Eli Lilly&#8230;<\/p>\n","protected":false},"author":1,"featured_media":12290,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[23],"tags":[],"class_list":{"0":"post-12289","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-finance"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.3 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Here\u2019s how Eli Lilly might bring a game-changing Alzheimer\u2019s drug to market | inFundPros<\/title>\n<meta name=\"description\" content=\"As part of the MarketWatch 50 series, Eleanor Laise interviewed Dr. Daniel Skovronsky, the chief scientific and medical officer at Eli Lilly &amp; 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