{"id":4540,"date":"2023-10-23T09:26:18","date_gmt":"2023-10-23T09:26:18","guid":{"rendered":"https:\/\/infundpros.com\/business\/roche-agrees-7-1bn-deal-for-telavant-to-boost-drug-pipeline\/"},"modified":"2023-10-23T09:26:18","modified_gmt":"2023-10-23T09:26:18","slug":"roche-agrees-7-1bn-deal-for-telavant-to-boost-drug-pipeline","status":"publish","type":"post","link":"https:\/\/infundpros.com\/?p=4540","title":{"rendered":"Roche agrees $7.1bn deal for Telavant to boost drug pipeline"},"content":{"rendered":"<div>\n<p>Unlock the Editor\u2019s Digest for free<\/p>\n<p class=\"article__content-sign-up-topic-description\"><span>Roula Khalaf, Editor of the FT, selects her favourite stories in this weekly newsletter.<\/span><\/p>\n<p><iframe class=\"article__content-sign-up-iframe close\" scrolling=\"no\" id=\"signUpIframe\" data-prev-url=\"\/register\/in-article-sign-up?ft-content-uuid=909ba009-9384-4889-b40d-664853e437b6\"><\/iframe><\/div>\n<div id=\"article-body\">\n<p>Roche plans to buy immunology company Telavant from Roivant Sciences and Pfizer for over $7bn, as the drugmaker\u2019s new chief executive seeks to replenish its drug pipeline.\u00a0<\/p>\n<p>The Swiss company will acquire the rights to develop and manufacture Telavant\u2019s potential drug for inflammatory bowel disease, which affects almost 8mn people worldwide. It will acquire the rights to sell it in the US, where there is a $15bn market for IBD, and in Japan. <\/p>\n<p>Thomas Schinecker, who took over as Roche chief executive in March, said the drug, which is ready to start a late-stage trial, had \u201ctransformational potential\u201d.\u00a0<\/p>\n<p>Roche will pay $7.1bn upfront and a near-term milestone payment of $150mn. Pfizer will keep the commercialisation rights outside the US and Japan. Roivant owns 75 per cent of Telavant, while Pfizer owns 25 per cent.\u00a0<\/p>\n<p>Schinecker said last month that the company was open to making large acquisitions, if they made financial sense. He was previously chief of the Roche diagnostics business, and is now focusing on improving the future of the pharmaceutical division with internal development and deals, after disappointments including two of its late-stage Alzheimer\u2019s drug trials, which ended in failure last year.<\/p>\n<p>This deal comes after Roche announced a partnership with Alnylam worth up to $2.8bn to work together on an innovative medicine for hypertension.\u00a0<\/p>\n<p>Large pharmaceutical companies are increasingly interested in immunology \u2014 tackling diseases often caused by an overactive immune system \u2014 because of the large number of affected patients. AbbVie\u2019s Humira, used for a range of autoimmune diseases, became the world\u2019s best-selling drug but has recently had its market exclusivity expire.<\/p>\n<p>Teresa Graham, chief executive of Roche\u2019s pharmaceutical division, said more patients suffered from diseases of the immune system than from cancer, and the current drugs did not serve them well. Now, she said, the science was starting to evolve rapidly.<\/p>\n<p>\u201cDespite advances in therapy, there really have been no cures for these diseases. They\u2019re incredibly impactful to individuals and to families. They put a lot of strain on healthcare systems,\u201d she told the Financial Times.\u00a0\u00a0<\/p>\n<p>\u201cAs we understand more and more about the biology of the human immune system, we will continue to find new and novel ways to target these diseases, and potentially, not only create a really meaningful benefit for individual patients, but also remove a lot of burden off of global healthcare systems.\u201d<\/p>\n<p>Roche said that Telavant\u2019s drug, known as RVT-3101, had the potential to be applied to conditions beyond inflammatory bowel disease, because the antibody tackles both inflammation and fibrosis.\u00a0<\/p>\n<p>In a phase-2b trial of patients with moderate to severe ulcerative colitis, a type of inflammatory bowel disease, it improved clinical remission by 36 per cent in 56 weeks, compared with placebo. The trial also showed that the drug was safe.<\/p>\n<p>Roivant Sciences, which has a portfolio of companies, was founded in 2014 by Vivek Ramaswamy, who is now running for US president. Ramaswamy owned a 7 per cent stake in the company, as of last month, but is no longer associated with running it.<\/p>\n<\/div>\n<p>Read the full article <a href=\"https:\/\/www.ft.com\/content\/909ba009-9384-4889-b40d-664853e437b6\" target=\"_blank\" rel=\"noopener\">here<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Unlock the Editor\u2019s Digest for free Roula Khalaf, Editor of the FT, selects her favourite stories in this weekly newsletter. Roche plans&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[22],"tags":[],"class_list":{"0":"post-4540","1":"post","2":"type-post","3":"status-publish","4":"format-standard","6":"category-business"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.3 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Roche agrees $7.1bn deal for Telavant to boost drug pipeline | inFundPros<\/title>\n<meta name=\"description\" content=\"Unlock the Editor\u2019s Digest for freeRoula Khalaf, Editor of the FT, selects her favourite stories in this weekly newsletter.Roche plans to buy immunology\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/infundpros.com\/?p=4540\" \/>\n<meta property=\"og:locale\" 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